Thorsten A. Kirschberg: search on Z-Library

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1

Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection

Link, John O., Taylor, James G., Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Keller, Terry, Yang, Zheng-Y

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

2

A New Class of Simplified Phorbol Ester Analogues: Synthesis and Binding to PKC and ηPKC-C1B (ηPKC-CRD2)

Wender, Paul A., Kirschberg, Thorsten A., Williams, Peter D., Bastiaans, Harold M. M., Irie, Kazuhiro

Journal:

Organic Letters

Year:

1999

Language:

english

File:

PDF, 61 KB

english, 1999

3

Novel, sulfonamide linked inhibitors of the hepatitis C virus NS3 protease

Kirschberg, Thorsten A., Squires, Neil H., Yang, Huiling, Corsa, Amoreena C., Tian, Yang, Tirunagari, Neeraj, Sheng, X. Christopher, Kim, Choung U.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 569 KB

english, 2014

4

Synthesis of 1′- C -Cyano Pyrimidine Nucleosides and Characterization as HCV Polymerase Inhibitors

Kirschberg, Thorsten A., Mish, Michael, Squires, Neil H., Zonte, Sebastian, Aktoudianakis, Evangelos, Metobo, Sammy, Butler, Thomas, Ju, Xie, Cho, Aesop, Ray, Adrian S., Kim, Choung U.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2015

Language:

english

File:

PDF, 980 KB

english, 2015

5

Reductive cyclization of α-cyclopropylketones with alkynyl- and aryl-tethered substituents

Maurizio Fagnoni, Philip Schmoldt, Thorsten Kirschberg, Jochen Mattay

Journal:

Year:

1998

Language:

english

File:

PDF, 1.10 MB

english, 1998

6

Arginine-Based Molecular Transporters: The Synthesis and Chemical Evaluation of Releasable Taxol-Transporter Conjugates

Kirschberg, Thorsten A., VanDeusen, Chris L., Rothbard, Jonathan B., Yang, Michael, Wender, Paul A.

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

7

Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase—Structure–activity relationships and crystallographic analysis

Thorsten A. Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C. Liclican, Damian J. McColl, Neil H. Squires, Eric B. Lansdon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 197 KB

english, 2008

8

Selective Thyroid Hormone Receptor Î² Agonists with Oxadiazolone Acid Isosteres

Kirschberg, Thorsten A., Jones, Christopher T., Xu, Yingzi, Fenaux, Martijn, Halcomb, Randall L., Wang, Yujin, Klucher, Kevin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2020

File:

PDF, 1.01 MB

2020

9

10.1038/81359

Rothbard, Jonathan B., Khavari, Paul A., Garlington, Sarah, Lin, Qun, Kirschberg, Thorsten, Kreider, Erik, McGrane, P. Leo, Wender, Paul A.

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 745 KB

english, 2000

10

Fragmentation-cyclization reactions by photoinduced electron transfer

Thorsten Kirschberg, Jochen Mattay

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 251 KB

english, 1994

11

Discovery of a 2′-fluoro-2′- C -methyl C -nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties

Kirschberg, Thorsten A., Metobo, Sammy, Clarke, Michael O., Aktoudianakis, Vangelis, Babusis, Darius, Barauskas, Ona, Birkus, Gabriel, Butler, Thomas, Byun, Daniel, Chin, Gregory, Doerffler, Edward, E

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 886 KB

english, 2017

12

Non-proteinogenic Amino Acid Containing Nucleotide Prodrug to Improve Oral Delivery of a Hepatitis C Virus Treatment

Feng, Joy Y., Wang, Ting, Park, Yeojin, Babusis, Darius, Birkus, Gabriel, Xu, Yili, Voitenleitner, Christian, Fenaux, Martijn, Yang, Huiling, Eng, Stacey, Tirunagari, Neeraj, Kirschberg, Thorsten, Cho

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2018

Language:

english

File:

PDF, 992 KB

english, 2018

13

Synthesis and characterization of 1′-C-cyano-2′-fluoro-2′-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors

Kirschberg, Thorsten A., Mish, Michael R., Zhang, Lijun, Squires, Neil H., Wang, Ke-Yu, Cho, Aesop, Feng, Joy Y., Fenaux, Martijn, Babusis, Darius, Park, Yeojin, Ray, Adrian S., Kim, Choung U.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

14

Photoinduced electron transfer (PET) in organic synthesis. [3 + 2]-type cycloaddition, cyclization and CC bond cleavage reactions

Evelyn Albrecht, Johannes Averdung, Eric W. Bischof, Andreas Heidbreder, Thorsten Kirschberg, Felix Müller, Jochen Mattay

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

1994

Language:

english

File:

PDF, 1.07 MB

english, 1994

15

Photoinduced Electron Transfer Reactions of α-Cyclopropyl- and α-Epoxy Ketones. Tandem Fragmentation−Cyclization to Bi-, Tri-, and Spirocyclic Ketones

Kirschberg, Thorsten, Mattay, Jochen

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 506 KB

english, 1996

16

Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH

William J. Watkins, James M. Chen, Aesop Cho, Lee Chong, Nicole Collins, Maria Fardis, Wei Huang, Magdeleine Hung, Thorsten Kirschberg, William A. Lee, Xiaohong Liu, William Thomas, Jie Xu, Ameneh Zey

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

17

RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

Kirschberg, Thorsten A., Balakrishnan, Mini, Squires, Neil H., Barnes, Tiffany, Brendza, Katherine M., Chen, Xiaowu, Eisenberg, Eugene J., Jin, Weili, Kutty, Nilima, Leavitt, Stephanie, Liclican, Albe

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.23 MB

english, 2009

18

Use of Benzofuran for Concomitant Protection of Aldehyde and Phenol Groups in the Preparation of Mycophenolic Acid Analogues

Fardis, Maria, Mertzman, Michael, Thomas, William, Kirschberg, Thorsten, Collins, Nicole, Polniaszek, Richard, Watkins, William J.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

19

Correction to Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection

Link, John O., Taylor, James G., Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Kellar, Terry, Yang, Zheng-Y

Journal:

Journal of Medicinal Chemistry

Year:

2016

File:

PDF, 107 KB

2016

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